Prevalencia y concordancia entre diagnóstico clínico y anatomopatológico de demencia en una clínica psicogeriátrica / Prevalence and concordance between the clinical and the post-mortem diagnosis of dementia in a psychogeriatric clinic

Introducción: Describir los tipos de demencia en una serie de pacientes valorados en una clínica psicogeriátrica y estimar el grado de acuerdo entre el diagnóstico clínico y el anatomopatológico. Material y métodos: Realizamos un análisis descriptivo de la prevalencia de los tipos de demencia entre los pacientes valorados en nuestro centro y establecemos el grado de concordancia entre el diagnóstico clínico y el anatomopatológico. Los diagnósticos se establecieron en función de los criterios diagnósticos vigentes en cada momento. Resultados: Ciento catorce casos cumplieron los criterios de inclusión. Los diagnósticos más frecuentes tanto a nivel clínico como anatomopatológico fueron enfermedad de Alzheimer y demencia mixta, pero la prevalencia se invirtió pasando de un 39% y 18% a nivel clínico a un 22% y 34% a nivel anatomopatológico respectivamente. La concordancia entre el diagnóstico clínico y el anatomopatológico fue de un 62% (IC 95%: 53-72%). Conclusiones: Casi un tercio de nuestros pacientes no tenía un diagnóstico certero en vida, fundamentalmente a expensas del infradiagnóstico a nivel clínico de la enfermedad cerebrovascular (AU)

Introduction: The aim of our study is to describe the types of dementia found in a series of patients and to estimate the level of agreement between the clinical diagnosis and post-mortem diagnosis. Material and Methods: We conducted a descriptive analysis of the prevalence of the types of dementia found in our series and we established the level of concordance between the clinical and the post-mortem diagnoses. The diagnosis was made based on current diagnostic criteria. Results: 114 cases were included. The most common clinical diagnoses both at a clinical and autopsy level were Alzheimer disease and mixed dementia but the prevalence was quite different. While at a clinical level, prevalence was 39% for Alzheimer disease and 18% for mixed dementia, in the autopsy level, prevalence was 22% and 34%, respectively. The agreement between the clinical and the autopsy diagnoses was 62% (95% CI 53-72%). Conclusions: Almost a third of our patients were not correctly diagnosed in vivo. The most common mistake was the underdiagnosis of cerebrovascular pathology (AU)

Prevalence and concordance between the clinical and the post-mortem diagnosis of dementia in a psychogeriatric clinic. / Prevalencia y concordancia entre diagnóstico clínico y anatomopatológico de demencia en una clínica psicogeriátrica.

INTRODUCTION: The aim of our study is to describe the types of dementia found in a series of patients and to estimate the level of agreement between the clinical diagnosis and post-mortem diagnosis. MATERIAL AND METHODS: We conducted a descriptive analysis of the prevalence of the types of dementia found in our series and we established the level of concordance between the clinical and the post-mortem diagnoses. The diagnosis was made based on current diagnostic criteria. RESULTS: 114 cases were included. The most common clinical diagnoses both at a clinical and autopsy level were Alzheimer disease and mixed dementia but the prevalence was quite different. While at a clinical level, prevalence was 39% for Alzheimer disease and 18% for mixed dementia, in the autopsy level, prevalence was 22% and 34%, respectively. The agreement between the clinical and the autopsy diagnoses was 62% (95% CI 53-72%). CONCLUSIONS: Almost a third of our patients were not correctly diagnosed in vivo. The most common mistake was the underdiagnosis of cerebrovascular pathology.